Day 2 :
- Special Session
Prince Sultan Cardiac Centre, Saudi Arabia
Title: Modulation of heart rate variability: A novel nonpharmacological modality for lowering blood pressure in hypertensive patients
Time : 10:00-11:00
Abdullah Al Abdulgader is the Professor of Congenital Cardiology/Electrophysiology and also General Directorate of Health. He has completed his undergraduate in King Faisal University 1991. He is founder and General Director in Prince Sultan Cardiac Centre, General Director of King Fahad Hospital. He has received many local and international compliments and awards. A large number of Congratulatory Letters from the Presidents of the various Universities in Saudi and local educational and academic authorities has been received by him. He has got Congratulatory Letter from the Royal Highness Prince Salman Ibn Abdul-Aziz and Crowned Prince of Saudi Arabia.
This study examined the efficacy of teaching emotional self-regulation techniques supported by heart rhythm coherence pattern (Heart Rate Variability modulation (HRV)) training as a means to quickly lower blood pressure (BP) in patients diagnosed with hypertension. To the best of our knowledge, an investigation of their ability to produce immediate reductions in BP had not been published in the medical literature. The study was a randomized controlled design with 62 hypertensive participants who were divided into three groups. An analysis of covariates was conducted to compare the effectiveness of three different interventions on reducing the participants’ BP. The modulation of HRV to coherence pattern was associated with a significantly greater reduction in mean arterial pressure in the two groups who used the intervention as compared with the relaxation-plus-medication group. Additionally, the group not taking medication that used the intervention also had a significantly greater reduction in systolic BP than the relaxation- plus-medication group. These results suggest that self-regulation techniques that incorporate the intentional generation of positive emotions to facilitate a shift into the psycho-physiological coherence state are an effective approach to lowering BP. Change in the physiological set-point for homeostatic regulation of BP is thought to be the underlying mechanism. Further studies should examine if large scale implementations of such heart-based coherence techniques could have a significant impact on reducing risk of mortality and morbidity in hypertensive patients.
- Session 2
University of Alexandria, Egypt
Time : 11:30-12:00
Moustafa Mohamed Nawar completed his MBBch in 1975, MSc cardiology 1980, and MD cardiology 1986.Currently he is the Prof. of Cardiology and Head of EP lab, Faculty of Medicine, Alexandria University.
Cardiac resynchronization therapy (CRT) has been used to treat advanced cases of heart failure. How to predict who will respond to CRT remains an important and largely unanswered question. To assess and identify the best predictors of CRT response.170 Patients with heart failure and LVEF<35% were included, the predictors of response assessed including preimplantation clinical, electrocardiographic and echocardiographic variables. CRT response was assessed after 6m.Independent pre implantation predictors of response were the QRS duration>150msec, non-ischemic cardiomyopathy, TAPSE>15 mm, sinus rhythm, absence of COPD and absence of history of renal disease. A new CRTscore to predict responders to CRTwas successfully developed. The score consists of maximum 9 point. The CRT response rate has been markedly different according to the CRTscore with very high response rate if CRTscore>6.The new CRTscore can be useful in patient selection in order to improve the CRT response rate. Validation of the score in different population is highly recommended.
Soraya Siabani has completed her Medical Doctorate (MD) from Kermanshah University of Medical Sciences (KUMS) in Iran at the age of 25 years, and her PhD from the University of Sydney Faculty Medicine in Australia 2015. She is working as a researcher and faculty member at KUMS now. Soraya has published more than 18 papers in reputed journals (Persian and English), and been serving as an editorial board member of Novelty in Biomedicine (NBM).
Congenital heart defects accounts for more than 30% of all major congenital anomalies worldwide. Regional factors play an important role in the prevalence and incidence of congenital anomalies. Congenital heart defects affects approximately 4-8 per 1000 live births worldwide. Iran is likely faced to a greater incidence of congenital anomalies including CHDs, due to specific cultural factors (e.g. consanguineous marriages) and being exposed to hazardous biochemical materials abused during periods of conflicts (1980-1988).The aim of this systematic review was to summarize the incidence, prevalence and mortality of CHDs in Iranian. We evaluate all related studies published in EMBASE, Web of Sciences, CINAHL, CINHAL, Google Scholar and PubMed from 2000 to 2015. In addition, we consider the studies conducted by Iranian researchers which are mostly published in the Persian (language) and therefore missed by international databases. Also references listed from relevant articles have been searched for related papers.
Prince Sultan Cardiac Centre, Saudi Arabia
Title: Extra cardiac anomalies (ECA) in 2020 subjects with congenital cardiovascular malformation (CCVM) and control: Etiological perspective
Time : 12:30-13:00
Abdullah Al Abdulgader is the Professor of Congenital Cardiology/Electrophysiology and also General Directorate of Health. He has completed his undergraduate in King Faisal University 1991. He is founder and general director in Prince Sultan Cardiac Centre, General Director of King Fahad Hospital. He has received many local and international compliments and awards. A large number of Congratulatory Letters from the Presidents of the various Universities in Saudi and local educational and academic authorities has been received by him. He has got Congratulatory Letter From the Royal Highness Prince Salman Ibn Abdulaziz and Crowned Prince of Saudi Arabia.
Association of Congenital Cardiac Malformation with Extra Cardiac Anomalies is well documented. The main objective of this investigation was to analyze the frequency of extra-cardiac malformations and the proportion of chromosome aberrations among live-born infants with Congenital Cardiac Malformation (CCM) in an attempt to generate hypothetical theories of CCM genesis. The study results showed that out of 1010 Congenital Cardiac Malformation (CCM) compared to 10101 normal individuals, 288 were affected by extra cardiac anomalies (28.5%). Atrio-ventricular Septal Defect (AVSD) was found to be the most common CCM associated with ECA (72%) while Dextro-Transposition of Great arteries (D-TGA) was the lowest (8.7%). Syndromes were the commonest extra cardiac anomalies (37%) with congenital cardiac malformation. Complex heart defects such as Hypo-plastic Left Heart syndrome (HLHS) and Double Outlet Right Ventricle (DORV) were infrequently associated with CCM. Statistically significant associations were found between some CCM and certain systems. CCM with ECA associations and incidence of frequent chromosomal aberrations in Saudi population reflect importance of underlying genetic factors which may have pleiotropic effects and shared common pathways. The directive nature of these epidemiological associations is crucial for guidance of our efforts in the genetic and epigenetic fields. In this context molecular and bioinformatics approaches to uncover regulatory gene networks may provide insights needed to understand cardiogenesis and Congenital Cardiac Malformation etiology in human.